Hatchet ribozyme structure and implications for cleavage mechanism

Small self-cleaving ribozymes catalyze site-specific cleavage of their own phosphodiester backbone with implications for viral genome replication, pre-mRNA processing, and alternative splicing. We report on the 2.1-Å crystal structure of the hatchet ribozyme product, which adopts a compact pseudosym...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Luqian, Falschlunger, Christoph, Huang, Kaiyi, Mairhofer, Elisabeth, Yuan, Shuguang, Wang, Juncheng, Patel, Dinshaw J., Micura, Ronald, Ren, Aiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561176/
https://www.ncbi.nlm.nih.gov/pubmed/31088965
http://dx.doi.org/10.1073/pnas.1902413116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561176/
https://www.ncbi.nlm.nih.gov/pubmed/31088965
http://dx.doi.org/10.1073/pnas.1902413116

Ejemplares similares