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CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis

Cell lineage specification is a tightly regulated process that is dependent on appropriate expression of lineage and developmental stage-specific transcriptional programs. Here, we show that Chromodomain Helicase DNA-binding protein 4 (CHD4), a major ATPase/helicase subunit of Nucleosome Remodeling...

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Detalles Bibliográficos
Autores principales: Arends, Tessa, Dege, Carissa, Bortnick, Alexandra, Danhorn, Thomas, Knapp, Jennifer R., Jia, Haiqun, Harmacek, Laura, Fleenor, Courtney J., Straign, Desiree, Walton, Kendra, Leach, Sonia M., Feeney, Ann J., Murre, Cornelis, O’Connor, Brian P., Hagman, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561196/
https://www.ncbi.nlm.nih.gov/pubmed/31085655
http://dx.doi.org/10.1073/pnas.1821301116