IKKβ slows Huntington’s disease progression in R6/1 mice

Neuroinflammation is an important contributor to neuronal pathology and death in neurodegenerative diseases and neuronal injury. Therapeutic interventions blocking the activity of the inflammatory kinase IKKβ, a key regulator of neuroinflammatory pathways, is protective in several animal models of n...

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Detalles Bibliográficos
Autores principales: Ochaba, Joseph, Fote, Gianna, Kachemov, Marketta, Thein, Soe, Yeung, Sylvia Y., Lau, Alice L., Hernandez, Sarah, Lim, Ryan G., Casale, Malcolm, Neel, Michael J., Monuki, Edwin S., Reidling, Jack, Housman, David E., Thompson, Leslie M., Steffan, Joan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561205/
https://www.ncbi.nlm.nih.gov/pubmed/31088970
http://dx.doi.org/10.1073/pnas.1814246116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561205/
https://www.ncbi.nlm.nih.gov/pubmed/31088970
http://dx.doi.org/10.1073/pnas.1814246116

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