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Imaging-based pooled CRISPR screening reveals regulators of lncRNA localization
Pooled-library CRISPR screening provides a powerful means to discover genetic factors involved in cellular processes in a high-throughput manner. However, the phenotypes accessible to pooled-library screening are limited. Complex phenotypes, such as cellular morphology and subcellular molecular orga...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561216/ https://www.ncbi.nlm.nih.gov/pubmed/31085639 http://dx.doi.org/10.1073/pnas.1903808116 |