Cargando…
Imaging-based pooled CRISPR screening reveals regulators of lncRNA localization
Pooled-library CRISPR screening provides a powerful means to discover genetic factors involved in cellular processes in a high-throughput manner. However, the phenotypes accessible to pooled-library screening are limited. Complex phenotypes, such as cellular morphology and subcellular molecular orga...
Autores principales: | Wang, Chong, Lu, Tian, Emanuel, George, Babcock, Hazen P., Zhuang, Xiaowei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561216/ https://www.ncbi.nlm.nih.gov/pubmed/31085639 http://dx.doi.org/10.1073/pnas.1903808116 |
Ejemplares similares
-
Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy
por: Potting, Christoph, et al.
Publicado: (2018) -
Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr
por: Zakany, Jozsef, et al.
Publicado: (2017) -
Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1–infected human macrophages
por: Boliar, Saikat, et al.
Publicado: (2019) -
LncRNA IDH1-AS1 links the functions of c-Myc and HIF1α via IDH1 to regulate the Warburg effect
por: Xiang, Shaoxun, et al.
Publicado: (2018) -
Faraday cage screening reveals intrinsic aspects of the van der Waals attraction
por: Li, Musen, et al.
Publicado: (2018)