Elasticity of individual protocadherin 15 molecules implicates tip links as the gating springs for hearing

Hair cells, the sensory receptors of the inner ear, respond to mechanical forces originating from sounds and accelerations. An essential feature of each hair cell is an array of filamentous tip links, consisting of the proteins protocadherin 15 (PCDH15) and cadherin 23 (CDH23), whose tension is thou...

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Detalles Bibliográficos
Autores principales: Bartsch, Tobias F., Hengel, Felicitas E., Oswald, Aaron, Dionne, Gilman, Chipendo, Iris V., Mangat, Simranjit S., El Shatanofy, Muhammad, Shapiro, Lawrence, Müller, Ulrich, Hudspeth, A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561218/
https://www.ncbi.nlm.nih.gov/pubmed/31072932
http://dx.doi.org/10.1073/pnas.1902163116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561218/
https://www.ncbi.nlm.nih.gov/pubmed/31072932
http://dx.doi.org/10.1073/pnas.1902163116

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