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Synapsins regulate α-synuclein functions

The normal function of α-synuclein (α-syn) remains elusive. Although recent studies suggest α-syn as a physiologic attenuator of synaptic vesicle (SV) recycling, mechanisms are unclear. Here, we show that synapsin—a cytosolic protein with known roles in SV mobilization and clustering—is required for...

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Detalles Bibliográficos
Autores principales: Atias, Merav, Tevet, Yaara, Sun, Jichao, Stavsky, Alexandra, Tal, Shani, Kahn, Joy, Roy, Subhojit, Gitler, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561288/
https://www.ncbi.nlm.nih.gov/pubmed/31110014
http://dx.doi.org/10.1073/pnas.1903054116