Role for polo-like kinase 4 in mediation of cytokinesis

The mitotic protein polo-like kinase 4 (PLK4) plays a critical role in centrosome duplication for cell division. By using immunofluorescence, we confirm that PLK4 is localized to centrosomes. In addition, we find that phospho-PLK4 (pPLK4) is cleaved and distributed to kinetochores (metaphase and ana...

Descripción completa

Detalles Bibliográficos
Autores principales: Press, Michael F., Xie, Bin, Davenport, Simon, Zhou, Yu, Guzman, Roberta, Nolan, Garry P., O’Brien, Neil, Palazzolo, Michael, Mak, Tak W., Brugge, Joan S., Slamon, Dennis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561306/
https://www.ncbi.nlm.nih.gov/pubmed/31097597
http://dx.doi.org/10.1073/pnas.1818820116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561306/
https://www.ncbi.nlm.nih.gov/pubmed/31097597
http://dx.doi.org/10.1073/pnas.1818820116

Ejemplares similares