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KR-12-a5 Reverses Adverse Effects of Lipopolysaccharides on HBMSC Osteogenic Differentiation by Influencing BMP/Smad and P38 MAPK Signaling Pathways

KR-12-a5 is an analogue of the antimicrobial peptide KR-12. Both of these two agents can play key effects in the treatment of infections such as osteomyelitis. Our previous work demonstrated that the osteogenic differentiation of human bone marrow mesenchymal stem cells (HBMSCs) can be enhanced by K...

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Detalles Bibliográficos
Autores principales: Li, Hui, Zhang, Shutao, Nie, Bin’en, Long, Teng, Qu, Xinhua, Yue, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561377/
https://www.ncbi.nlm.nih.gov/pubmed/31231225
http://dx.doi.org/10.3389/fphar.2019.00639