Cargando…

KR-12-a5 Reverses Adverse Effects of Lipopolysaccharides on HBMSC Osteogenic Differentiation by Influencing BMP/Smad and P38 MAPK Signaling Pathways

KR-12-a5 is an analogue of the antimicrobial peptide KR-12. Both of these two agents can play key effects in the treatment of infections such as osteomyelitis. Our previous work demonstrated that the osteogenic differentiation of human bone marrow mesenchymal stem cells (HBMSCs) can be enhanced by K...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Hui, Zhang, Shutao, Nie, Bin’en, Long, Teng, Qu, Xinhua, Yue, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561377/ https://www.ncbi.nlm.nih.gov/pubmed/31231225 http://dx.doi.org/10.3389/fphar.2019.00639

Ejemplares similares

The antimicrobial peptide KR-12 promotes the osteogenic differentiation of human bone marrow stem cells by stimulating BMP/SMAD signaling
por: Li, Hui, et al.
Publicado: (2018)

Approaches to Biofunctionalize Polyetheretherketone for Antibacterial: A Review
por: Wang, Yihan, et al.
Publicado: (2022)

KR-12-a6 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells via BMP/SMAD signaling
por: Fu, Lanqing, et al.
Publicado: (2020)

All-trans retinoic acid restored the osteogenic ability of BMP9 in osteosarcoma through the p38 MAPK pathway
por: Wu, Nian, et al.
Publicado: (2019)

Effects of staphylococcal infection and aseptic inflammation on bone mass and biomechanical properties in a rabbit model
por: Li, Hui, et al.
Publicado: (2019)

Nectandrin A Enhances the BMP-Induced Osteoblastic Differentiation and Mineralization by Activation of p38 MAPK-Smad Signaling Pathway
por: Kim, Do Yeon, et al.
Publicado: (2013)

CircRFWD2 Promotes Osteogenic Differentiation of human Dental Pulp Stem Cells by Targeting miR-6817-5p Through BMP-Smad and p38 MAPK Pathway
por: Huang, Xinqi, et al.
Publicado: (2021)

Gadolinium-doped bioglass scaffolds promote osteogenic differentiation of hBMSC via the Akt/GSK3β pathway and facilitate bone repair in vivo
por: Zhu, Dao-Yu, et al.
Publicado: (2019)

P38 and ERK1/2 MAPKs Act in Opposition to Regulate BMP9-Induced Osteogenic Differentiation of Mesenchymal Progenitor Cells
por: Zhao, Yingze, et al.
Publicado: (2012)

Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation
por: Sautchuk, Rubens, et al.
Publicado: (2022)

Retraction: P38 and ERK1/2 MAPKs Act in Opposition to Regulate BMP9-Induced Osteogenic Differentiation of Mesenchymal Progenitor Cells
Publicado: (2018)

IGF1 potentiates BMP9-induced osteogenic differentiation in mesenchymal stem cells through the enhancement of BMP/Smad signaling
por: Chen, Liang, et al.
Publicado: (2016)

Genistein Promotion of Osteogenic Differentiation through BMP2/SMAD5/RUNX2 Signaling
por: Dai, Jin, et al.
Publicado: (2013)

miR-21 synergizes with BMP9 in osteogenic differentiation by activating the BMP9/Smad signaling pathway in murine multilineage cells
por: SONG, QILING, et al.
Publicado: (2015)

Comparison of osteogenic differentiation induced by siNoggin and pBMP-2 delivered by lipopolysaccharide-amine nanopolymersomes and underlying molecular mechanisms
por: Huang, Mingdi, et al.
Publicado: (2019)

Notch signaling pathway promotes osteogenic differentiation of mesenchymal stem cells by enhancing BMP9/Smad signaling
por: Cao, Junjie, et al.
Publicado: (2017)

BMP7 retards peripheral myelination by activating p38 MAPK in Schwann cells
por: Liu, Xiaoyu, et al.
Publicado: (2016)

Induction of Angiogenesis by Matrigel Coating of VEGF-Loaded PEG/PCL-Based Hydrogel Scaffolds for hBMSC Transplantation
por: Jung, Yeon Joo, et al.
Publicado: (2015)

Shape dynamics in neutron-rich Kr isotopes: Coulomb excitation of $^{92}Kr$, $^{94}Kr$ and $^{96}Kr$
por: Albers, M, et al.
Publicado: (2013)

Lifetime measurement in $^{74}$Kr and $^{76}$Kr
por: Görgen, A, et al.
Publicado: (2005)

Role of p38 MAPK and STAT3 in lipopolysaccharide-stimulated mouse alveolar macrophages
por: MENG, AIHONG, et al.
Publicado: (2014)

Free or fixed state of nHAP differentially regulates hBMSC morphology and osteogenesis through the valve role of ITGA7
por: Bao, Fangyuan, et al.
Publicado: (2022)

BMP9-Induced Survival Effect in Liver Tumor Cells Requires p38MAPK Activation
por: García-Álvaro, María, et al.
Publicado: (2015)

Bone infection site targeting nanoparticle-antibiotics delivery vehicle to enhance treatment efficacy of orthopedic implant related infection
por: Nie, Bin'en, et al.
Publicado: (2022)

Paeoniflorin improves myocardial injury via p38 MAPK/NF-KB p65 inhibition in lipopolysaccharide-induced mouse
por: Wang, Shaojun, et al.
Publicado: (2021)

Modulation of osteogenic and myogenic differentiation by a phytoestrogen formononetin via p38MAPK-dependent JAK-STAT and Smad-1/5/8 signaling pathways in mouse myogenic progenitor cells
por: Soundharrajan, Ilavenil, et al.
Publicado: (2019)

Association of Bone Morphogenetic Protein (BMP)/Smad Signaling Pathway with Fracture Healing and Osteogenic Ability in Senile Osteoporotic Fracture in Humans and Rats
por: Liu, De-Bao, et al.
Publicado: (2018)

Effect of the p38 MAPK inhibitor doramapimod on the systemic inflammatory response to intravenous lipopolysaccharide in horses
por: Bauquier, Jennifer, et al.
Publicado: (2020)

Inhibition of HDAC6 alleviating lipopolysaccharide-induced p38MAPK phosphorylation and neuroinflammation in mice
por: Song, Yuanjian, et al.
Publicado: (2019)

Lipoteichoic Acid and Lipopolysaccharides Are Affected by p38 and Inflammatory Markers and Modulate Their Promoting and Inhibitory Effects on Osteogenic Differentiation
por: Ishihata, Kiyohide, et al.
Publicado: (2022)

Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities
por: Berasi, Stephen P, et al.
Publicado: (2011)

Inhibition of actin polymerization decreases osteogeneic differentiation of mesenchymal stem cells through p38 MAPK pathway
por: Sonowal, Himangshu, et al.
Publicado: (2013)

Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway
por: Cui, Qi, et al.
Publicado: (2019)

A standalone bioreactor system to deliver compressive load under perfusion flow to hBMSC-seeded 3D chitosan-graphene templates
por: Lovecchio, Joseph, et al.
Publicado: (2019)

Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB
por: Huang, Xia, et al.
Publicado: (2017)

miR-765 inhibits the osteogenic differentiation of human bone marrow mesenchymal stem cells by targeting BMP6 via regulating the BMP6/Smad1/5/9 signaling pathway
por: Wang, Tao, et al.
Publicado: (2020)

COX-2 promotes the osteogenic potential of BMP9 through TGF-β1/p38 signaling in mesenchymal stem cells
por: Deng, Yan, et al.
Publicado: (2021)

The decay of $^{76}$Kr
por: Lode, D, et al.
Publicado: (1973)

The decay of $^{75}$Kr
por: Roeckl, E, et al.
Publicado: (1974)

Jiawei Yanghe Decoction Regulates Bone-Lipid Balance through the BMP-SMAD Signaling Pathway to Promote Osteogenic Differentiation of Bone Mesenchymal Stem Cells
por: Luo, Yunfeng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_igbcujgk5g4nf0u7h1peh4mcld