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Mitofusin2, as a Protective Target in the Liver, Controls the Balance of Apoptosis and Autophagy in Acute-on-Chronic Liver Failure

Aim: Acute-on-chronic liver failure (ACLF) is closely related to mitochondrial dysfunction. Previous studies showed the vital role of mitofusin2 (Mfn2) in the regulation of mitochondrial function. However, the effect of Mfn2 on ACLF remains unknown. As one of mitochondrial-related pathways, BNIP3-me...

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Detalles Bibliográficos
Autores principales: Xue, Ran, Yang, Jing, Jia, Lin, Zhu, Xuemin, Wu, Jing, Zhu, Yueke, Meng, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561379/
https://www.ncbi.nlm.nih.gov/pubmed/31231215
http://dx.doi.org/10.3389/fphar.2019.00601