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An interferon-like small chemical compound CDM-3008 suppresses hepatitis B virus through induction of interferon-stimulated genes

Oral administration of nucleotide analogues and injection of interferon-α (IFNα) are used to achieve immediate suppression in replication of hepatitis B virus (HBV). Nucleotide analogs and IFNα inhibit viral polymerase activity and cause long-term eradication of the virus at least in part through re...

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Detalles Bibliográficos
Autores principales: Furutani, Yutaka, Toguchi, Mariko, Shiozaki-Sato, Yumi, Qin, Xian-Yang, Ebisui, Etsuko, Higuchi, Shoko, Sudoh, Masayuki, Suzuki, Harukazu, Takahashi, Nobuaki, Watashi, Koichi, Wakita, Takaji, Kakeya, Hideaki, Kojima, Soichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561549/
https://www.ncbi.nlm.nih.gov/pubmed/31188831
http://dx.doi.org/10.1371/journal.pone.0216139