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Structural prediction of RNA switches using conditional base-pair probabilities

An RNA switch triggers biological functions by toggling between two conformations. RNA switches include bacterial riboswitches, where ligand binding can stabilize a bound structure. For RNAs with only one stable structure, structural prediction usually just requires a straightforward free energy min...

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Detalles Bibliográficos
Autores principales: Manzourolajdad, Amirhossein, Spouge, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561571/
https://www.ncbi.nlm.nih.gov/pubmed/31188853
http://dx.doi.org/10.1371/journal.pone.0217625