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Structural prediction of RNA switches using conditional base-pair probabilities
An RNA switch triggers biological functions by toggling between two conformations. RNA switches include bacterial riboswitches, where ligand binding can stabilize a bound structure. For RNAs with only one stable structure, structural prediction usually just requires a straightforward free energy min...
Autores principales: | Manzourolajdad, Amirhossein, Spouge, John L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561571/ https://www.ncbi.nlm.nih.gov/pubmed/31188853 http://dx.doi.org/10.1371/journal.pone.0217625 |
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