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Effectiveness assessment of riluzole in the prevention of oxaliplatin-induced peripheral neuropathy: RILUZOX-01: protocol of a randomised, parallel, controlled, double-blind and multicentre study by the UNICANCER-AFSOS Supportive Care intergroup

INTRODUCTION: Most patients (>70%) experience acute neuropathic symptoms shortly after oxaliplatin infusions. These symptoms are not always resolved between infusions. Overall, 30%–50% of patients suffer from chronic oxaliplatin-induced peripheral neuropathy (OIPN). This cumulative and dose-depen...

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Detalles Bibliográficos
Autores principales: Kerckhove, Nicolas, Busserolles, Jérome, Stanbury, Trevor, Pereira, Bruno, Plence, Valérie, Bonnetain, Franck, Krakowski, Ivan, Eschalier, Alain, Pezet, Denis, Balayssac, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561607/
https://www.ncbi.nlm.nih.gov/pubmed/31182448
http://dx.doi.org/10.1136/bmjopen-2018-027770