Cargando…

Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway

Emerging studies have indicated that leucine-rich repeat kinase 2 (LRRK2) is associated with thyroid cancer (TC). The present study investigated the effect of LRRK2 on the cell cycle and apoptosis in TC, and examined the underlying mechanisms in vitro. To screen TC-associated differentially expresse...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Zheng-Cai, Chen, Xiao-Jun, Zhou, Qi, Gong, Xiao-Hua, Chen, Xiong, Wu, Wen-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561619/
https://www.ncbi.nlm.nih.gov/pubmed/31180559
http://dx.doi.org/10.3892/ijo.2019.4816