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Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway
Emerging studies have indicated that leucine-rich repeat kinase 2 (LRRK2) is associated with thyroid cancer (TC). The present study investigated the effect of LRRK2 on the cell cycle and apoptosis in TC, and examined the underlying mechanisms in vitro. To screen TC-associated differentially expresse...
Autores principales: | Jiang, Zheng-Cai, Chen, Xiao-Jun, Zhou, Qi, Gong, Xiao-Hua, Chen, Xiong, Wu, Wen-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561619/ https://www.ncbi.nlm.nih.gov/pubmed/31180559 http://dx.doi.org/10.3892/ijo.2019.4816 |
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