Class I histone deacetylase inhibitor suppresses vasculogenic mimicry by enhancing the expression of tumor suppressor and anti-angiogenesis genes in aggressive human TNBC cells

Triple-negative breast cancer (TNBC) cells form angiogenesis-independent vessel-like structures to survive, known as vasculogenic mimicry (VM), contributing to a poor prognosis for cancer patients. Nuclear localized class I histone deacetylases (HDACs) enzymes, particularly HDACs 1, 2, 3 deacetylate...

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Detalles Bibliográficos
Autores principales: Maiti, Aparna, Qi, Qianya, Peng, Xuan, Yan, Li, Takabe, Kazuaki, Hait, Nitai C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561627/
https://www.ncbi.nlm.nih.gov/pubmed/31059004
http://dx.doi.org/10.3892/ijo.2019.4796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561627/
https://www.ncbi.nlm.nih.gov/pubmed/31059004
http://dx.doi.org/10.3892/ijo.2019.4796

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