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Direct visualization of the E. coli Sec translocase engaging precursor proteins in lipid bilayers

Escherichia coli exports proteins via a translocase comprising SecA and the translocon, SecYEG. Structural changes of active translocases underlie general secretory system function, yet directly visualizing dynamics has been challenging. We imaged active translocases in lipid bilayers as a function...

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Detalles Bibliográficos
Autores principales: Sanganna Gari, Raghavendar Reddy, Chattrakun, Kanokporn, Marsh, Brendan P., Mao, Chunfeng, Chada, Nagaraju, Randall, Linda L., King, Gavin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561738/
https://www.ncbi.nlm.nih.gov/pubmed/31206019
http://dx.doi.org/10.1126/sciadv.aav9404