Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression

The Polycomb system modifies chromatin and plays an essential role in repressing gene expression to control normal mammalian development. However, the components and mechanisms that define how Polycomb protein complexes achieve this remain enigmatic. Here, we use combinatorial genetic perturbation c...

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Detalles Bibliográficos
Autores principales: Fursova, Nadezda A., Blackledge, Neil P., Nakayama, Manabu, Ito, Shinsuke, Koseki, Yoko, Farcas, Anca M., King, Hamish W., Koseki, Haruhiko, Klose, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561741/
https://www.ncbi.nlm.nih.gov/pubmed/31029541
http://dx.doi.org/10.1016/j.molcel.2019.03.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561741/
https://www.ncbi.nlm.nih.gov/pubmed/31029541
http://dx.doi.org/10.1016/j.molcel.2019.03.024

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