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Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression
The Polycomb system modifies chromatin and plays an essential role in repressing gene expression to control normal mammalian development. However, the components and mechanisms that define how Polycomb protein complexes achieve this remain enigmatic. Here, we use combinatorial genetic perturbation c...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561741/ https://www.ncbi.nlm.nih.gov/pubmed/31029541 http://dx.doi.org/10.1016/j.molcel.2019.03.024 |