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DamC reveals principles of chromatin folding in vivo without crosslinking and ligation

Current understanding of chromosome folding largely relies on chromosome conformation capture (3C)-based experiments, where chromosomal interactions are detected as ligation products after chromatin crosslinking. To measure chromosome structure in vivo, quantitatively and without crosslinking and li...

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Detalles Bibliográficos
Autores principales: Redolfi, Josef, Zhan, Yinxiu, Valdes-Quezada, Christian, Kryzhanovska, Mariya, Guerreiro, Isabel, Iesmantavicius, Vytautas, Pollex, Tim, Grand, Ralph S., Mulugeta, Eskeatnaf, Kind, Jop, Tiana, Guido, Smallwood, Sebastien A., de Laat, Wouter, Giorgetti, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561777/
https://www.ncbi.nlm.nih.gov/pubmed/31133702
http://dx.doi.org/10.1038/s41594-019-0231-0