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Multiscale Immune Selection and the Transmission-Diversity Feedback in Antigenically Diverse Pathogen Systems

Antigenic diversity is commonly used by pathogens to enhance their transmission success. Within-host clonal antigenic variation helps to maintain long infectious periods, whereas high levels of allelic diversity at the population level significantly expand the pool of susceptible individuals. Divers...

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Detalles Bibliográficos
Autores principales: Holding, Thomas, Valletta, John Joseph, Recker, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561780/
https://www.ncbi.nlm.nih.gov/pubmed/30444661
http://dx.doi.org/10.1086/699535