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Multiscale Immune Selection and the Transmission-Diversity Feedback in Antigenically Diverse Pathogen Systems
Antigenic diversity is commonly used by pathogens to enhance their transmission success. Within-host clonal antigenic variation helps to maintain long infectious periods, whereas high levels of allelic diversity at the population level significantly expand the pool of susceptible individuals. Divers...
Autores principales: | Holding, Thomas, Valletta, John Joseph, Recker, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561780/ https://www.ncbi.nlm.nih.gov/pubmed/30444661 http://dx.doi.org/10.1086/699535 |
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