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Transcriptomic profiling reveals p53 as a key regulator of doxorubicin-induced cardiotoxicity

Doxorubicin is an important anticancer drug in the clinic. Unfortunately, it causes cumulative and dose-dependent cardiotoxic side effects. As the population of cancer survivors who have been exposed to treatment continues to grow, there is increased interest in assessing the long-term cardiac effec...

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Detalles Bibliográficos
Autores principales: McSweeney, K. Melodi, Bozza, William P., Alterovitz, Wei-Lun, Zhang, Baolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561911/
https://www.ncbi.nlm.nih.gov/pubmed/31231550
http://dx.doi.org/10.1038/s41420-019-0182-6