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Transcriptomic profiling reveals p53 as a key regulator of doxorubicin-induced cardiotoxicity
Doxorubicin is an important anticancer drug in the clinic. Unfortunately, it causes cumulative and dose-dependent cardiotoxic side effects. As the population of cancer survivors who have been exposed to treatment continues to grow, there is increased interest in assessing the long-term cardiac effec...
Autores principales: | McSweeney, K. Melodi, Bozza, William P., Alterovitz, Wei-Lun, Zhang, Baolin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561911/ https://www.ncbi.nlm.nih.gov/pubmed/31231550 http://dx.doi.org/10.1038/s41420-019-0182-6 |
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