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DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass

Mitochondrial quality control is essential in highly structured cells such as neurons and muscles. In skeletal muscle the mitochondrial fission proteins are reduced in different physiopathological conditions including ageing sarcopenia, cancer cachexia and chemotherapy-induced muscle wasting. Howeve...

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Detalles Bibliográficos
Autores principales: Favaro, Giulia, Romanello, Vanina, Varanita, Tatiana, Andrea Desbats, Maria, Morbidoni, Valeria, Tezze, Caterina, Albiero, Mattia, Canato, Marta, Gherardi, Gaia, De Stefani, Diego, Mammucari, Cristina, Blaauw, Bert, Boncompagni, Simona, Protasi, Feliciano, Reggiani, Carlo, Scorrano, Luca, Salviati, Leonardo, Sandri, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561930/
https://www.ncbi.nlm.nih.gov/pubmed/31189900
http://dx.doi.org/10.1038/s41467-019-10226-9