The transcription factor Slug represses p16(Ink4a) and regulates murine muscle stem cell aging

Activation of the p16(Ink4a)-associated senescence pathway during aging breaks muscle homeostasis and causes degenerative muscle disease by irreversibly dampening satellite cell (SC) self-renewal capacity. Here, we report that the zinc-finger transcription factor Slug is highly expressed in quiescen...

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Detalles Bibliográficos
Autores principales: Zhu, Pei, Zhang, Chunping, Gao, Yongxing, Wu, Furen, Zhou, Yalu, Wu, Wen-Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561969/
https://www.ncbi.nlm.nih.gov/pubmed/31189923
http://dx.doi.org/10.1038/s41467-019-10479-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561969/
https://www.ncbi.nlm.nih.gov/pubmed/31189923
http://dx.doi.org/10.1038/s41467-019-10479-4

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