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Impact of sample preparation upon intracellular metabolite measurements in 3D cell culture systems

INTRODUCTION: Interest in cell culture metabolomics has increased greatly in recent years because of its many potential applications and advantages (e.g., in toxicology). The first critical step for exploring the cellular metabolome is sample preparation. For metabolomics studies, an ideal sample pr...

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Detalles Bibliográficos
Autores principales: Mathon, Caroline, Bovard, David, Dutertre, Quentin, Sendyk, Sandra, Bentley, Mark, Hoeng, Julia, Knorr, Arno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561993/
https://www.ncbi.nlm.nih.gov/pubmed/31190156
http://dx.doi.org/10.1007/s11306-019-1551-0