Cargando…

The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary disease

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death worldwide with no curative therapy. A non-canonical Notch ligand, DNER, has been recently identified in GWAS to associate with COPD severity, but its function and contribution to COPD is unknown. METHODS: DN...

Descripción completa

Detalles Bibliográficos
Autores principales: Ballester-López, Carolina, Conlon, Thomas M., Ertüz, Zeynep, Greiffo, Flavia R., Irmler, Martin, Verleden, Stijn E., Beckers, Johannes, Fernandez, Isis E., Eickelberg, Oliver, Yildirim, Ali Önder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562022/
https://www.ncbi.nlm.nih.gov/pubmed/31060902
http://dx.doi.org/10.1016/j.ebiom.2019.03.054