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IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states
BACKGROUND: Antibody Fc-driven engagement of macrophages is critical for evoking cellular activation and effector functions and influencing tumour-associated macrophage (TAM) recruitment. We previously reported that IgE class antibodies promote restriction of cancer growth in rodent models associate...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562024/ https://www.ncbi.nlm.nih.gov/pubmed/30956175 http://dx.doi.org/10.1016/j.ebiom.2019.03.080 |