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A pan-cancer analysis of synonymous mutations

Synonymous mutations have been viewed as silent mutations, since they only affect the DNA and mRNA, but not the amino acid sequence of the resulting protein. Nonetheless, recent studies suggest their significant impact on splicing, RNA stability, RNA folding, translation or co-translational protein...

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Detalles Bibliográficos
Autores principales: Sharma, Yogita, Miladi, Milad, Dukare, Sandeep, Boulay, Karine, Caudron-Herger, Maiwen, Groß, Matthias, Backofen, Rolf, Diederichs, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562042/
https://www.ncbi.nlm.nih.gov/pubmed/31189880
http://dx.doi.org/10.1038/s41467-019-10489-2