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A pan-cancer analysis of synonymous mutations
Synonymous mutations have been viewed as silent mutations, since they only affect the DNA and mRNA, but not the amino acid sequence of the resulting protein. Nonetheless, recent studies suggest their significant impact on splicing, RNA stability, RNA folding, translation or co-translational protein...
Autores principales: | Sharma, Yogita, Miladi, Milad, Dukare, Sandeep, Boulay, Karine, Caudron-Herger, Maiwen, Groß, Matthias, Backofen, Rolf, Diederichs, Sven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562042/ https://www.ncbi.nlm.nih.gov/pubmed/31189880 http://dx.doi.org/10.1038/s41467-019-10489-2 |
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