NF-κB in the crosshairs: Rethinking an old riddle

Constitutive NF-κB signalling has been implicated in the pathogenesis of most human malignancies and virtually all non-malignant pathologies. Accordingly, the NF-κB pathway has been aggressively pursued as an attractive therapeutic target for drug discovery. However, the severe on-target toxicities...

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Detalles Bibliográficos
Autores principales: Bennett, Jason, Capece, Daria, Begalli, Federica, Verzella, Daniela, D’Andrea, Daniel, Tornatore, Laura, Franzoso, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562234/
https://www.ncbi.nlm.nih.gov/pubmed/29277662
http://dx.doi.org/10.1016/j.biocel.2017.12.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562234/
https://www.ncbi.nlm.nih.gov/pubmed/29277662
http://dx.doi.org/10.1016/j.biocel.2017.12.020

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