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TMEM16F/Anoctamin 6 in Ferroptotic Cell Death

Ca(2+) activated Cl(−) channels (TMEM16A; ANO1) support cell proliferation and cancer growth. Expression of TMEM16A is strongly enhanced in different types of malignomas. In contrast, TMEM16F (ANO6) operates as a Ca(2+) activated chloride/nonselective ion channel and scrambles membrane phospholipids...

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Detalles Bibliográficos
Autores principales: Ousingsawat, Jiraporn, Schreiber, Rainer, Kunzelmann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562394/
https://www.ncbi.nlm.nih.gov/pubmed/31060306
http://dx.doi.org/10.3390/cancers11050625