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An In Vitro System for Evaluating Molecular Targeted Drugs Using Lung Patient-Derived Tumor Organoids

Patient-derived tumor organoids (PDOs) represent a promising preclinical cancer model that better replicates disease, compared with traditional cell culture models. We have established PDOs from various human tumors to accurately and efficiently recapitulate the tissue architecture and function. Mol...

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Detalles Bibliográficos
Autores principales: Takahashi, Nobuhiko, Hoshi, Hirotaka, Higa, Arisa, Hiyama, Gen, Tamura, Hirosumi, Ogawa, Mayu, Takagi, Kosuke, Goda, Kazuhito, Okabe, Naoyuki, Muto, Satoshi, Suzuki, Hiroyuki, Shimomura, Kenju, Watanabe, Shinya, Takagi, Motoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562414/
https://www.ncbi.nlm.nih.gov/pubmed/31137590
http://dx.doi.org/10.3390/cells8050481