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Effect of Disease-Associated Germline Mutations on Structure Function Relationship of DNA Methyltransferases
Despite a large body of evidence supporting the role of aberrant DNA methylation in etiology of several human diseases, the fundamental mechanisms that regulate the activity of mammalian DNA methyltransferases (DNMTs) are not fully understood. Recent advances in whole genome association studies have...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562416/ https://www.ncbi.nlm.nih.gov/pubmed/31091831 http://dx.doi.org/10.3390/genes10050369 |