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Effect of Disease-Associated Germline Mutations on Structure Function Relationship of DNA Methyltransferases

Despite a large body of evidence supporting the role of aberrant DNA methylation in etiology of several human diseases, the fundamental mechanisms that regulate the activity of mammalian DNA methyltransferases (DNMTs) are not fully understood. Recent advances in whole genome association studies have...

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Detalles Bibliográficos
Autores principales:	Norvil, Allison B., Saha, Debapriya, Saleem Dar, Mohd, Gowher, Humaira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562416/ https://www.ncbi.nlm.nih.gov/pubmed/31091831 http://dx.doi.org/10.3390/genes10050369

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