Huzhangoside A Suppresses Tumor Growth through Inhibition of Pyruvate Dehydrogenase Kinase Activity

Aerobic glycolysis is one of the important metabolic characteristics of many malignant tumors. Pyruvate dehydrogenase kinase (PDHK) plays a key role in aerobic glycolysis by phosphorylating the E1α subunit of pyruvate dehydrogenase (PDH). Hence, PDHK has been recognized as a molecular target for can...

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Detalles Bibliográficos
Autores principales: Kwak, Choong-Hwan, Lee, Jung-Hee, Kim, Eun-Yeong, Han, Chang Woo, Kim, Keuk-Jun, Lee, Hanna, Cho, MyoungLae, Jang, Se Bok, Kim, Cheorl-Ho, Chung, Tae-Wook, Ha, Ki-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562422/
https://www.ncbi.nlm.nih.gov/pubmed/31126094
http://dx.doi.org/10.3390/cancers11050712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562422/
https://www.ncbi.nlm.nih.gov/pubmed/31126094
http://dx.doi.org/10.3390/cancers11050712

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