Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells

Pheochromocytomas and paragangliomas (PPGLs) with activated pseudohypoxic pathways are associated with an immature catecholamine phenotype and carry a higher risk for metastasis. For improved understanding of the underlying mechanisms we investigated the impact of hypoxia and pseudohypoxia on catech...

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Detalles Bibliográficos
Autores principales: Bechmann, Nicole, Poser, Isabel, Seifert, Verena, Greunke, Christian, Ullrich, Martin, Qin, Nan, Walch, Axel, Peitzsch, Mirko, Robledo, Mercedes, Pacak, Karel, Pietzsch, Jens, Richter, Susan, Eisenhofer, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562431/
https://www.ncbi.nlm.nih.gov/pubmed/31035382
http://dx.doi.org/10.3390/cancers11050594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562431/
https://www.ncbi.nlm.nih.gov/pubmed/31035382
http://dx.doi.org/10.3390/cancers11050594

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