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The Key Roles of PTEN in T-Cell Acute Lymphoblastic Leukemia Development, Progression, and Therapeutic Response

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive blood cancer that comprises 10–15% of pediatric and ~25% of adult ALL cases. Although the curative rates have significantly improved over the past 10 years, especially in pediatric patients, T-ALL remains a challenge from a therapeutic poi...

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Detalles Bibliográficos
Autores principales: Martelli, Alberto M., Paganelli, Francesca, Fazio, Antonietta, Bazzichetto, Chiara, Conciatori, Fabiana, McCubrey, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562458/
https://www.ncbi.nlm.nih.gov/pubmed/31064074
http://dx.doi.org/10.3390/cancers11050629