Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines

Targeting metabolism represents a possible successful approach to treat cancer. Dichloroacetate (DCA) is a drug known to divert metabolism from anaerobic glycolysis to mitochondrial oxidative phosphorylation by stimulation of PDH. In this study, we investigated the response of two pancreatic cancer...

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Detalles Bibliográficos
Autores principales: Tataranni, Tiziana, Agriesti, Francesca, Pacelli, Consiglia, Ruggieri, Vitalba, Laurenzana, Ilaria, Mazzoccoli, Carmela, Della Sala, Gerardo, Panebianco, Concetta, Pazienza, Valerio, Capitanio, Nazzareno, Piccoli, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562462/
https://www.ncbi.nlm.nih.gov/pubmed/31109089
http://dx.doi.org/10.3390/cells8050478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562462/
https://www.ncbi.nlm.nih.gov/pubmed/31109089
http://dx.doi.org/10.3390/cells8050478

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