The α9α10 Nicotinic Acetylcholine Receptor Antagonist αO-Conotoxin GeXIVA[1,2] Alleviates and Reverses Chemotherapy-Induced Neuropathic Pain

Oxaliplatin is a third-generation platinum drug and is widely used as a first-line therapy for the treatment of colorectal cancer (CRC). However, a large number of patients receiving oxaliplatin develop dose-limiting painful neuropathy. Here, we report that αO-conotoxin GeXIVA[1,2], a highly potent...

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Detalles Bibliográficos
Autores principales: Wang, Huanbai, Li, Xiaodan, Zhangsun, Dongting, Yu, Gang, Su, Ruibin, Luo, Sulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562493/
https://www.ncbi.nlm.nih.gov/pubmed/31060282
http://dx.doi.org/10.3390/md17050265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562493/
https://www.ncbi.nlm.nih.gov/pubmed/31060282
http://dx.doi.org/10.3390/md17050265

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