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3D-Organotypic Cultures to Unravel Molecular and Cellular Abnormalities in Atopic Dermatitis and Ichthyosis Vulgaris

Atopic dermatitis (AD) is characterized by dry and itchy skin evolving into disseminated skin lesions. AD is believed to result from a primary acquired or a genetically-induced epidermal barrier defect leading to immune hyper-responsiveness. Filaggrin (FLG) is a protein found in the cornified envelo...

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Detalles Bibliográficos
Autores principales: Leman, Géraldine, Moosbrugger-Martinz, Verena, Blunder, Stefan, Pavel, Petra, Dubrac, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562513/
https://www.ncbi.nlm.nih.gov/pubmed/31121896
http://dx.doi.org/10.3390/cells8050489