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The Vav GEF Family: An Evolutionary and Functional Perspective

Vav proteins play roles as guanosine nucleotide exchange factors for Rho GTPases and signaling adaptors downstream of protein tyrosine kinases. The recent sequencing of the genomes of many species has revealed that this protein family originated in choanozoans, a group of unicellular organisms from...

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Detalles Bibliográficos
Autores principales: Rodríguez-Fdez, Sonia, Bustelo, Xosé R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562523/
https://www.ncbi.nlm.nih.gov/pubmed/31100928
http://dx.doi.org/10.3390/cells8050465