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The Vav GEF Family: An Evolutionary and Functional Perspective
Vav proteins play roles as guanosine nucleotide exchange factors for Rho GTPases and signaling adaptors downstream of protein tyrosine kinases. The recent sequencing of the genomes of many species has revealed that this protein family originated in choanozoans, a group of unicellular organisms from...
Autores principales: | Rodríguez-Fdez, Sonia, Bustelo, Xosé R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562523/ https://www.ncbi.nlm.nih.gov/pubmed/31100928 http://dx.doi.org/10.3390/cells8050465 |
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