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The Biosynthesis of Rare Homo-Amino Acid Containing Variants of Microcystin by a Benthic Cyanobacterium

Microcystins are a family of chemically diverse hepatotoxins produced by distantly related cyanobacteria and are potent inhibitors of eukaryotic protein phosphatases 1 and 2A. Here we provide evidence for the biosynthesis of rare variants of microcystin that contain a selection of homo-amino acids b...

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Detalles Bibliográficos
Autores principales: Shishido, Tânia Keiko, Jokela, Jouni, Humisto, Anu, Suurnäkki, Suvi, Wahlsten, Matti, Alvarenga, Danillo O., Sivonen, Kaarina, Fewer, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562525/
https://www.ncbi.nlm.nih.gov/pubmed/31067786
http://dx.doi.org/10.3390/md17050271