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The Biosynthesis of Rare Homo-Amino Acid Containing Variants of Microcystin by a Benthic Cyanobacterium
Microcystins are a family of chemically diverse hepatotoxins produced by distantly related cyanobacteria and are potent inhibitors of eukaryotic protein phosphatases 1 and 2A. Here we provide evidence for the biosynthesis of rare variants of microcystin that contain a selection of homo-amino acids b...
Autores principales: | Shishido, Tânia Keiko, Jokela, Jouni, Humisto, Anu, Suurnäkki, Suvi, Wahlsten, Matti, Alvarenga, Danillo O., Sivonen, Kaarina, Fewer, David P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562525/ https://www.ncbi.nlm.nih.gov/pubmed/31067786 http://dx.doi.org/10.3390/md17050271 |
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