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Actinomycin V Inhibits Migration and Invasion via Suppressing Snail/Slug-Mediated Epithelial-Mesenchymal Transition Progression in Human Breast Cancer MDA-MB-231 Cells In Vitro

Actinomycin V, an analog of actinomycin D produced by the marine-derived actinomycete Streptomyces sp., possessing a 4-ketoproline instead of a 4-proline in actinomycin D. In this study, the involvement of snail/slug-mediated epithelial-mesenchymal transition (EMT) in the anti-migration and -invasio...

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Detalles Bibliográficos
Autores principales: Lin, Shiqi, Zhang, Caiyun, Liu, Fangyuan, Ma, Jiahui, Jia, Fujuan, Han, Zhuo, Xie, Weidong, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562598/
https://www.ncbi.nlm.nih.gov/pubmed/31137656
http://dx.doi.org/10.3390/md17050305