Cancer Cells Tune the Signaling Pathways to Empower de Novo Synthesis of Nucleotides

Cancer cells exhibit a dynamic metabolic landscape and require a sufficient supply of nucleotides and other macromolecules to grow and proliferate. To meet the metabolic requirements for cell growth, cancer cells must stimulate de novo nucleotide synthesis to obtain adequate nucleotide pools to supp...

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Detalles Bibliográficos
Autores principales: Villa, Elodie, Ali, Eunus S., Sahu, Umakant, Ben-Sahra, Issam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562601/
https://www.ncbi.nlm.nih.gov/pubmed/31108873
http://dx.doi.org/10.3390/cancers11050688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562601/
https://www.ncbi.nlm.nih.gov/pubmed/31108873
http://dx.doi.org/10.3390/cancers11050688

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